Sheffield Institute for
Translational Neuroscience

Our Vision

The key vision of SITraN is to develop an international centre of excellence for basic through to applied research in neurodegenerative disease to complement the existing partnerships of academic research groups, government and charitable research funding bodies the pharmaceutical industry and the health care sector.

The Sheffield Institute for Translational Neuroscience (SITraN) is an essential development
in the fight against motor neuron disease and other common neurodegenerative disorders of the motor system. As yet no single Institution anywhere in the world has developed the necessary critical mass and facilities to exploit the potential of modern neuroscience, the 'post-genome' era, and exciting developments in biomedical therapeutics with specific focus on this devastating group of illnesses.

Centres of excellence for neurodegneration research across the globe have achieved considerable progress, but none are effectively poised to develop these advances to the full.

The establishment of SITraN in Sheffield offers the opportunity for a coordinated approach to the development and clinical trialling of new therapies based on rational targets of proven preclinical effectiveness.


Professor Dame Pamela Shaw