Sheffield Institute for
Translational Neuroscience

Dr Esther Hobson MRCP PhD FHEA

Senior Lecturer, University of Sheffield

Neurology Speciality Registrar, Royal Hallamshire Hospital, Sheffield

 


Research Interests

She is a member of the motor neuron disorders clinical studies group at the Sheffield Neuroscience NIHR BRC led by Professor Pamela Shaw and Professor Chris McDermott. 

Her core aim of research is on improving the quality and standard of care provided to people living with long-term neurological conditions, both patients and their family and carers. She is am particularly interested in complex interventions, digital technology, and evidence based care. She has experience in randomised controlled trials of therapies including novel genetic therapies as well as feasibility and implementation studies of complex interventions. She used mixed method approaches as well as person-centred design to ensure users are at the heart of effective NHS services.

Telehealth in motor neuron disease 

This project is currently funded by MND Scotland, previously funded by NIHR Research and the Motor Neurone Disease Association. It is an international multicentre implementation study of TiM (telehealth in MND). It aims to develop a digital service to support patients and their carers to gain access to a high standard of multidisciplinary care.

Improving NIV clinical services in MND

I co-lead an NIHR Research for Patient Benefit funded study which has developed evidenced based tools to help staff help their patients with motor neurone disease get the most out of non-invasive ventilation.

Other research interests

Other interests including improving the way in which we manage other symptoms of motor neurone disease and deliver education and information to people living with, and caring for people with neurological diseases.  This includes the development of the award winning website www.mytube.mymnd.org.uk which translates evidence from a prospective study of gastrostomy feeding, led by SITraN, into information designed for patients and carers to help support them thinking about and using gastrostomy feeding.

Current Projects

I was lucky enough to be awarded a National Institute for Health Research funded doctoral fellowship.  This enabled me to work together with the clinical team at SITraN and Sheffield School of Health and Related Research to develop and test a handheld device that communicates with their MND care team. 

Since then I have been working as an NIHR clinical lecturer using the learning from this fellowship to develop digital healthcare for a wider range or neurological conditions.

I co-lead an NIHR Research for Patient Benefit study aimed at developing evidenced based tools to help staff help their patients with motor neurone disease get the most out of non-invasive ventilation.

My other interests are improving the way in which we manage other symptoms of motor neurone disease and deliver education and information to people living with and caring for people with neurological diseases.  I was involved with the development of the award winning website www.mytubemymnd.org.uk which translates evidence from a prospective study of gastrostomy feeding, led by SITraN, into information designed for patients and carers to help support them thinking about and using gastrostomy feeding.

 

Publications

Perry RJ, Tamborska A, Singh B, Craven B, Marigold R, Arthur-Farraj P, Yeo JM, Zhang L, Hassan-Smith G, Jones M, Hutchcroft C, Hobson E, Warcel D, White D, Ferdinand P, Webb A, Solomon T, Scully M, Werring DJ, Roffe C; CVT After Immunisation Against COVID-19 (CAIAC) collaborators. Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study. Lancet. 2021 Sep 25;398(10306):1147-1156. doi: 10.1016/S0140-6736(21)01608-1. Epub 2021 Aug 6. PMID: 34370972; PMCID: PMC8346241.

Hobson, E V, Baird WO, Bradburn M, Cooper CL, Mawson S, Quinn Q, Shaw PJ, Walsh, T, McDermott CJ. “Using Telehealth in Motor Neuron Disease to Increase Access to Specialist Multidisciplinary Care: a UK-Based Pilot and Feasibility Study.” BMJ Open (2019).  http://doi:10.1136/bmjopen-2018-028525

Hobson, E V, Baird WO, Bradburn M, Cooper CL, Mawson S, Quinn Q, Shaw PJ, Walsh, T, McDermott CJ.  “Process Evaluation and Exploration of Telehealth in Motor Neuron Disease in a UK Specialist Centre.” BMJ Open (2019) http://doi:10.1136/bmjopen-2018-028526

Baxter SK, Johnson M, Clowes M, O'Brien D, Norman P, Stavroulakis T, Bianchi S, Elliott M, McDermott CJ*, and Hobson E* (*joint senior authors). “Optimizing the Noninvasive Ventilation Pathway for Patients with Amyotrophic Lateral Sclerosis/Motor Neuron Disease: a Systematic Review..” Amyotrophic Lateral Scler & Frontotemp Degen (2019). http://doi:10.1080/21678421.2019.1627372

Musson, L S, McDermott CJ, Hobson EV. “Exploring Patient and Public Involvement in Motor Neuron Disease Research..” Amyotrophic Lateral Scler & Frontotemp Degen (2019). http://doi:10.1080/21678421.2019.1643373

O'Brien, D, Stavroulakis T, Baxter S, Norman P, Bianchi S, Elliott M, Johnson M, Clowes M, Garcia-Sanchez A, Hobson* EV, McDermott CJ* (*joint senior authors) . “The Optimisation of Noninvasive Ventilation in Amyotrophic Lateral Sclerosis: a Systematic Review.” European Respiratory Journal  54, (2019). http://doi:10.1183/13993003.00261-2019

Hobson, EV, Baird WO, Partridge R, Cooper CL, Mawson S, Quinn A, Shaw PJ, Walsh T, Wolstenholme D, and Mcdermott CJ. “The TiM System: Developing a Novel Telehealth Service to Improve Access to Specialist Care in Motor Neurone Disease Using User-Centered Design.” Amyotrophic Lateral Scler & Frontotemp Degen (2018) http://doi:10.1080/21678421.2018.1440408

Waller, R., Goodall, E. F., Milo, M., Cooper-Knock, J., Da Costa, M., Hobson, E., et al. (2017). Serum miRNAs miR-206, 143-3p and 374b-5p as potential biomarkers for amyotrophic lateral sclerosis (ALS). Neurobiology of Aging. http://doi.org/10.1016/j.neurobiolaging.2017.03.027

White, S., Hobson, E. V., & Soreny, C. The development of the myTube website. Clinical Nutrition Focus (2017).

Hobson, E. V., Fazal, S., Shaw, P. J., & McDermott, CJ. “Anything that makes life’s journey better.” Exploring the use of digital technology by people living with motor neurone disease. Amyotrophic Lateral Scler & Frontotemp Degen (2017) http://doi.org/10.1080/21678421.2017.1288253

Hobson, E. V., & McDermott, C. J. Supportive and symptomatic management of amyotrophic lateral sclerosis. Nature Reviews Neurology (2016) http://doi.org/10.1038/nrneurol.2016.111

Hobson, E. V., Harwood, C. A., McDermott, C. J., & Shaw, P. J.. Clinical aspects of motor neurone disease. Medicine, (2016). http://doi.org/10.1016/j.mpmed.2016.06.004

McGeachan, A. J., Hobson, E. V., Al-Chalabi, A., Stephenson, J., Chandran, S., Crawley, F., et al. (2016). A multicentre evaluation of oropharyngeal secretion management practices in amyotrophic lateral sclerosis. Amyotrophic Lateral Scler & Frontotemp Degen http://doi.org/10.1080/21678421.2016.1221433

Hobson, E. V., Baird, W. O., Cooper, C. L., Mawson, S., Shaw, P. J., & McDermott, C. J. Using technology to improve access to specialist care in amyotrophic lateral sclerosis: A systematic review. Amyotrophic Lateral Scler & Frontotemp Degen (2016) http://doi.org/10.3109/21678421.2016.1165255

Nicholls*, Z., Hobson*, E., Martindale, J., & Shaw, P. J. Diagnosis of spinal xanthomatosis by next-generation sequencing: identifying a rare, treatable mimic of hereditary spastic paraparesis. Practical Neurology.  (*joint first author)  (2015) http://doi.org/10.1136/practneurol-2015-001117

McGeachan, A. J., Hobson, E. V., Shaw, P. J., & McDermott, C. J. Developing an outcome measure for excessive saliva management in MND and an evaluation of saliva burden in Sheffield. Amyotrophic Lateral Scler & Frontotemp Degen (2014). http://doi.org/10.3109/21678421.2014.951942

Hobson, E. V., McGeachan, A., Al-Chalabi, A., Chandran, S., Crawley, F., Dick, D., et al. Management of sialorrhoea in motor neuron disease: a survey of current UK practice. Amyotrophic Lateral Scler & Frontotemp Degen (2013) http://doi.org/10.3109/21678421.2013.790452

Hobson, E. V., Craven, I., & Blank, S. C. Posterior reversible encephalopathy syndrome: a truly treatable neurologic illness. Peritoneal Dialysis International : (2012). http://doi.org/10.3747/pdi.2012.00152

Hobson, E. V.. Medicine: a challenge for life. The Clinical Teacher, (2011). http://doi.org/10.1111/j.1743-498X.2011.00500.x

Baron-Cohen, S., Wheelwright, S., Burtenshaw, A., & Hobson, E. Mathematical Talent is Linked to Autism. Human Nature (2007)

http://doi.org/10.1007/s12110-007-9014-0

Biography

I undertook my pre-clinical medical training at St Catherine’s College, Cambridge University and achieved a first class degree in Experimental Psychology in 2003. I moved to Green College, Oxford University where I graduated from my clinical medical training with a Proxime Accessit award in 2006 whilst spending much of my time coxing the winning 2005 lightweight mens’ boatrace crew.  I undertook my junior doctor training in Oxfordshire and South Yorkshire before becoming a neurology registrar at the Royal Hallamshire Hospital in 2010.  I entered the NIHR academic training programme, completing a PhD between 2014 and 2018 before becoming a clinical lecturer.

Outside of medicine I enjoy mountain biking and exploring the beautiful outdoors around Sheffield. 

 

Awards

National Institute for Health Academic Clinical Fellowship, University of Sheffield, 2012-2014

National Institute for Health Doctoral Research Fellowship, University of Sheffield 2014-2017

National Institute for Health Clinical Lecturer in Neurology, University of Sheffield 2018-

 

Teaching Interests

Course co-lead for the MSc in Clinical Neurology at the University of Sheffield. She supervises undergraduate, postgraduate and doctoral research students. I have an interest in curriculum and teaching innovation and the use of digital learning for healthcare professionals.

 

Contact Details

Department of Neuroscience
SITraN
University of Sheffield
385a Glossop Road
Sheffield
S10 2HQ

E: e.hobson@sheffield.ac.uk

Administrator: Rebecca Brown
T: +44 (0) 114 2222261
E: rebecca.brown@sheffield.ac.uk

Clinical Secretaries:

Royal Hallamshire Hospital
zoe.hamilton1@nhs.net
0114 2712306

Doncaster Royal Infirmary
debra.webster@nhs.net
01909 572712